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Spyre Therapeutics, Inc. Common Stock (SYRE) Stock

NASDAQ · SYRE
Trade SYRE

Key stats

Market cap
$10.14B
Price / Earnings ratio
-37.6x
EPS (TTM)
-$2.78
Volume
Loading
52-week high
$110.64
52-week low
$21.63

Source: third-party data provider, as of November 13, 2026

Compare with SYRE

Recent news

Zacks Investment Research

Spyre's Anti-IL-23 Antibody Meets Goal in Ulcerative Colitis Study

SYRESeptember 9, 2026
Zacks Investment Research

Spyre Therapeutics (SYRE) Down 16.6% Since Last Earnings Report: Can It Rebound?

SYRESeptember 3, 2026
Zacks Investment Research

SYRE Stock Sinks After Mixed SKYWAY Study Data in Rheumatoid Arthritis

SYREAugust 26, 2026
Investors Business Daily

Spyre Plunges, While This Setback Isn't Shaking Analysts

SYREAugust 26, 2026

Technical indicators

RSI 14
64.24
MACD 12/26/9
4.45
EMA 9 of MACD
3.18
MACD histogram
1.27
SMA 50
$90.83
Price above SMA 50
EMA 50
$93.75
Price above EMA 50
SMA 200
$75.97
Price above SMA 200
EMA 200
$72.94
Price above EMA 200

Calculated by Gotrade from daily closing prices, as of November 11, 2026. Technical data, not a recommendation.

Analyst ratings

Analyst consensus: Buy

Based on 6 analyst ratings

Strong Sell0
Sell0
Hold0
Buy6
Strong Buy0

Third-party analyst opinion, not a recommendation from Gotrade.

Financials

Performance

Revenue
Net income
Net margin %
2021
2022
2023
2024
2025
22M15M7M0

Debt & Balance Sheet

Total assets
Total liabilities
2021
2022
2023
2024
2025
933M616M308M0

Revenue to Profit

2025
$0.0
Revenue
$0.0
Cost of revenue
$0.0
Gross profit
$0.0
Operating expenses
$-155.2M
Net income

Earnings

No data available

Source: third-party data provider

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AC IMMUNE SA
ACAD
ACADIA Pharma
ADPT
Adaptive Biotech

FAQ

Buying Spyre Therapeutics, Inc. Common Stock (SYRE) stock is now easy and instant through the Gotrade app.
  1. Download the Gotrade app from the App Store or Google Play.
  2. Create an account and verify your identity.
  3. Make a deposit.
  4. Search for the code "SYRE", then tap "Trade".
  5. Tap the "Buy" button.
  6. Enter the amount you want to buy. You have two options:
    1. Buy SYRE by number of shares.
    2. Buy fractional shares in dollars, starting from $1.
  7. Swipe up to confirm your order, and you're done!
On Gotrade, you don't have to buy a full share. With fractional shares, you can start investing in Spyre Therapeutics, Inc. Common Stock from just $1. A small budget shouldn't stop you from building a US stock portfolio.
At the moment, Spyre Therapeutics, Inc. Common Stock (SYRE) does not pay dividends because it focuses on reinvesting profits for company growth (a growth stock). However, you can still potentially earn profit from share price increases (capital gains). Track SYRE's performance via the price chart in the Gotrade app.
Gotrade is the trading name of Gotrade Securities Inc., which is registered with and supervised by the Labuan Financial Services Authority (LFSA).
You can place an order any time. It goes through when the US market (NYSE/NASDAQ) opens: 9:30 AM to 4:00 PM New York time, Monday to Friday. Pre-market and after-hours trading are open too.
The market is closed on US public holidays. The Gotrade app shows whether the market is open.
There's no single perfect answer, but common approaches include:
  • Compare valuation (e.g., P/E, P/S) against historical averages or competitors.
  • Review revenue and earnings growth.
  • Check margins and cash flow.
  • Evaluate business outlook and the company's position within its industry.
You can combine fundamental analysis with an investing strategy that matches your risk profile. All of the information above can be viewed directly in the Gotrade app.
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